Here is the direct and brief version on how to install Drupal 6.22 in Ubuntu Desktop 11.10.

1) Install LAMP server

i) Open command line terminal.
ii) Type: sudo su
iii) Provide password.
iv) Type: tasksel
v) Choose 'lamp server' to install.
vi) Start apache server: service apache2 reload
vii) Add virtual site: cp /etc/apache2/sites-available/default /etc/apache2/sites-available/website-name-directory
viii) Enable new website:
- cd /etc/apache2/sites-available/
- a2ensite website-name-directory

2) Drupal installation.

i) Create database for drupal (in mysql).
ii) Download drupal and extract it.
iii) Copy to /var/www/your-website-directory
iv) Open web browser and begin drupal installation.
v) All should be well accept 'cron' and 'GD library'.

3) Install GD library. Type: apt-get install php5-gd

4) Restart web server. Type: service apache2 reload

5) For cron, just 'run cron manually' or use poormanscron module.

6) Reload drupal 'status report' page to confirm.

7) Enable clean URL:

i)Check rewrite_module: root@ubuntu:/home/kkcj# apache2ctl -M

ii) Enable rewrite_module: root@ubuntu:/home/kkcj# a2enmod rewrite

iii) Restart web server: root@ubuntu:/home/kkcj# service apache2 reload

iv) Set directory permission: root@ubuntu:/etc/apache2# vim sites-enabled/website-name-directory

Options Indexes FollowSymLinks MultiViews
AllowOverride All
Order allow,deny
allow from all

Options Indexes FollowSymLinks MultiViews
AllowOverride All
Order allow,deny
allow from all

ScriptAlias /cgi-bin/ /usr/lib/cgi-bin/

AllowOverride All
Options +ExecCGI -MultiViews +SymLinksIfOwnerMatch
Order allow,deny
Allow from all

v) Set directory permission: root@ubuntu:/etc/apache2# vim sites-enabled/000-default

Options Indexes FollowSymLinks MultiViews
AllowOverride All
Order allow,deny
allow from all

Options Indexes FollowSymLinks MultiViews
AllowOverride All
Order allow,deny
allow from all

ScriptAlias /cgi-bin/ /usr/lib/cgi-bin/

AllowOverride All
Options +ExecCGI -MultiViews +SymLinksIfOwnerMatch
Order allow,deny
Allow from all

9) Restart apache again:
service apache2 reload

10) Troubleshooting

1) Included in .htaccess:

RewriteEngine on
RewriteBase /
RewriteCond %{REQUEST_FILENAME} !-f
RewriteCond %{REQUEST_FILENAME} !-d
RewriteRule ^(.*)$ index.php?q=$1 [L,QSA]

# Note:
# Change 'RewriteRule ^(.*)$ index.php?q=$1 [L,QSA]' to 'RewriteRule ^(.*)$ website-directory-name/index.php?q=$1 [L,QSA]' sometimes work on some system depends on configuration.
# Change 'RewriteBase /' to 'RewriteBase /website-name-directory' depends on configuration.

2) Check RewriteBase in /etc/apache2/sites-enabled/website-name-directory and .htacess:

# RewriteBase website-name-directory

or

# RewriteBase /

Remove comment (#) based on your configuration.